accession uid title organization taxonomy sra geo cell line culture media library preparation kit source_name time treatment xenograft SAMN05832102 5832102 SUM159xenograft_mouse3_2mpktrametinib30mpkIBET151_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716656 GSM2330655 SUM159 breast carcinoma cell line: xenograft 48h 2mpk trametinib 30mpkIBET151 SUM159 breast carcinoma cell line xenograft SAMN05832103 5832103 SUM159xenograft_mouse2_2mpktrametinib30mpkIBET151_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716653 GSM2330654 SUM159 breast carcinoma cell line: xenograft 48h 2mpk trametinib 30mpkIBET151 SUM159 breast carcinoma cell line xenograft SAMN05832104 5832104 SUM159xenograft_mouse2_2mpktrametinib_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716651 GSM2330651 SUM159 breast carcinoma cell line: xenograft 48h 2mpk trametinib SUM159 breast carcinoma cell line xenograft SAMN05832108 5832108 SUM229pos_DMSO_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716622 GSM2330622 SUM229 breast carcinoma cell line, EpCAM/CD49f positive subpopulation EpCAM/CD49f positive SUM229 breast carcinoma subpopulation 24h DMSO SAMN05832118 5832118 SUM229neg_30nMtrametinib_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716625 GSM2330625 SUM229 breast carcinoma cell line, EpCAM/CD49f negative subpopulation EpCAM/CD49f negative SUM229 breast carcinoma subpopulation 24h 30nM trametinib SAMN05832119 5832119 SUM229neg_DMSO_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716623 GSM2330624 SUM229 breast carcinoma cell line, EpCAM/CD49f negative subpopulation EpCAM/CD49f negative SUM229 breast carcinoma subpopulation 24h DMSO SAMN05832125 5832125 SUM229pos_30nMtrametinib_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716624 GSM2330623 SUM229 breast carcinoma cell line, EpCAM/CD49f positive subpopulation EpCAM/CD49f positive SUM229 breast carcinoma subpopulation 24h 30nM trametinib SAMN05832126 5832126 SUM159_100nM_trametinib_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716631 GSM2330631 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib SAMN05832127 5832127 SUM159_DMSO_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716629 GSM2330630 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h DMSO SAMN05832128 5832128 SUM159_300nMJQ1_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716632 GSM2330632 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 300nM JQ1 SAMN05832129 5832129 SUM159_100nMtrametinib300nMJQ1_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716637 GSM2330637 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib 300nM JQ1 SAMN05832130 5832130 SUM159_300nMJQ1_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716636 GSM2330636 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 300nM JQ1 SAMN05832131 5832131 SUM159_100nM_trametinib_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716635 GSM2330635 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib SAMN05832132 5832132 SUM159_DMSO_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716634 GSM2330634 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h DMSO SAMN05832133 5832133 SUM159_100nMtrametinib300nMJQ1_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716633 GSM2330633 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib 300nM JQ1 SAMN05832134 5832134 Figure3_HCC1806_10nMtrametinib300nMJQ1_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716645 GSM2330645 HCC1806 breast carcinoma cell line HCC1806 breast carcinoma cell line 48h 10nM trametinib 300nM JQ1 SAMN05832135 5832135 Figure3_HCC1806_DMSO_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716642 GSM2330642 HCC1806 breast carcinoma cell line HCC1806 breast carcinoma cell line 48h DMSO SAMN05832136 5832136 SUM159_100nMtrametinib300nMJQ1_24h_replicate3 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716641 GSM2330641 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib 300nM JQ1 SAMN05832137 5832137 SUM159_300nMJQ1_24h_replicate3 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716640 GSM2330640 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 300nM JQ1 SAMN05832138 5832138 SUM159_100nM_trametinib_24h_replicate3 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716639 GSM2330639 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib SAMN05832139 5832139 SUM159_DMSO_24h_replicate3 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716638 GSM2330638 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h DMSO SAMN05832140 5832140 Figure3_HCC1806_300nMJQ1_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716644 GSM2330644 HCC1806 breast carcinoma cell line HCC1806 breast carcinoma cell line 48h 300nM JQ1 SAMN05832141 5832141 Figure3_HCC1806_10nMtrametinib_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716643 GSM2330643 HCC1806 breast carcinoma cell line HCC1806 breast carcinoma cell line 48h 10nM trametinib SAMN05832142 5832142 Figure7_SUM159_100nMtrametinib500nMIBET151_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716649 GSM2330649 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib 500nM IBET151 SAMN05832143 5832143 Figure7_SUM159_500nMIBET151_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716648 GSM2330648 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 500nM IBET151 SAMN05832144 5832144 Figure7_SUM159_100nMtrametinib3uMSGCCBP30_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716647 GSM2330647 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 100nM trametinib 3uMSGCCBP30 SAMN05832145 5832145 SUM159xenograft_mouse1_2mpktrametinib_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716650 GSM2330650 SUM159 breast carcinoma cell line: xenograft 48h 2mpk trametinib SUM159 breast carcinoma cell line xenograft SAMN05832146 5832146 Figure7_SUM159_3uMSGCCBP30_24h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716646 GSM2330646 SUM159 breast carcinoma cell line SUM159 breast carcinoma cell line 24h 3uMSGCCBP30 SAMN05832147 5832147 SUM159xenograft_mouse3_control_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716661 GSM2330661 SUM159 breast carcinoma cell line: xenograft 48h control SUM159 breast carcinoma cell line xenograft SAMN05832148 5832148 SUM159xenograft_mouse2_control_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716660 GSM2330660 SUM159 breast carcinoma cell line: xenograft 48h control SUM159 breast carcinoma cell line xenograft SAMN05832149 5832149 SUM159xenograft_mouse3_2mpktrametinib_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716652 GSM2330652 SUM159 breast carcinoma cell line: xenograft 48h 2mpk trametinib SUM159 breast carcinoma cell line xenograft SAMN05832150 5832150 SUM159xenograft_mouse1_2mpktrametinib30mpkIBET151_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716654 GSM2330653 SUM159 breast carcinoma cell line: xenograft 48h 2mpk trametinib 30mpkIBET151 SUM159 breast carcinoma cell line xenograft SAMN05832151 5832151 SUM159xenograft_mouse1_control_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716659 GSM2330659 SUM159 breast carcinoma cell line: xenograft 48h control SUM159 breast carcinoma cell line xenograft SAMN05832152 5832152 SUM159xenograft_mouse3_30mpkIBET151_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716658 GSM2330658 SUM159 breast carcinoma cell line: xenograft 48h 30mpkIBET151 SUM159 breast carcinoma cell line xenograft SAMN05832153 5832153 SUM159xenograft_mouse2_30mpkIBET151_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716657 GSM2330657 SUM159 breast carcinoma cell line: xenograft 48h 30mpkIBET151 SUM159 breast carcinoma cell line xenograft SAMN05832154 5832154 SUM159xenograft_mouse1_30mpkIBET151_48h Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1716655 GSM2330656 SUM159 breast carcinoma cell line: xenograft 48h 30mpkIBET151 SUM159 breast carcinoma cell line xenograft SAMN06233963 6233963 WHIM12_500nMtrametinib_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937697 GSM2459932 PDX breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit WHIM12_500nMtrametinib_24h SAMN06233964 6233964 WHIM12_500nMtrametinib_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937696 GSM2459931 PDX breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit WHIM12_500nMtrametinib_24h SAMN06233965 6233965 WHIM12_DMSO_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937695 GSM2459930 PDX breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit WHIM12_DMSO_24h SAMN06233966 6233966 WHIM12_DMSO_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937694 GSM2459929 PDX breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit WHIM12_DMSO_24h SAMN06233967 6233967 HS578T_500nMtrametinib_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937693 GSM2459928 HS578T breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HS578T_500nMtrametinib_24h SAMN06233968 6233968 HS578T_500nMtrametinib_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937692 GSM2459927 HS578T breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HS578T_500nMtrametinib_24h SAMN06233969 6233969 HS578T_DMSO_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937691 GSM2459926 HS578T breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HS578T_DMSO_24h SAMN06233970 6233970 HS578T_DMSO_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937690 GSM2459925 HS578T breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HS578T_DMSO_24h SAMN06233971 6233971 SUM159_500nMtrametinib_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937689 GSM2459924 SUM159 breast carcinoma cell line DMEM/F12 1:1 supplemented with 5% FBS, 5 µg/ml insulin, 1 µg/ml hydrocortisone KAPA Stranded mRNAseq kit SUM159_500nMtrametinib_24h SAMN06233972 6233972 SUM159_500nMtrametinib_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937688 GSM2459923 SUM159 breast carcinoma cell line DMEM/F12 1:1 supplemented with 5% FBS, 5 µg/ml insulin, 1 µg/ml hydrocortisone KAPA Stranded mRNAseq kit SUM159_500nMtrametinib_24h SAMN06233973 6233973 MDAMB468_500nMtrametinib_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937687 GSM2459922 MDAMB468 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit MDAMB468_500nMtrametinib_24h SAMN06233974 6233974 MDAMB468_500nMtrametinib_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937686 GSM2459921 MDAMB468 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit MDAMB468_500nMtrametinib_24h SAMN06233975 6233975 MDAMB468_DMSO_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937685 GSM2459920 MDAMB468 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit MDAMB468_DMSO_24h SAMN06233976 6233976 MDAMB468_DMSO_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937684 GSM2459919 MDAMB468 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit MDAMB468_DMSO_24h SAMN06233977 6233977 SUM149pos_500nMtrametinib_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937683 GSM2459918 EpCAM/CD49f positive SUM149 breast carcinoma subpopulation HuMEC supplemented with 5% FBS and Gibco defined HuMEC supplements KAPA Stranded mRNAseq kit SUM149pos_500nMtrametinib_24h SAMN06233978 6233978 SUM149pos_500nMtrametinib_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937682 GSM2459917 EpCAM/CD49f positive SUM149 breast carcinoma subpopulation HuMEC supplemented with 5% FBS and Gibco defined HuMEC supplements KAPA Stranded mRNAseq kit SUM149pos_500nMtrametinib_24h SAMN06233979 6233979 SUM149pos_DMSO_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937681 GSM2459916 EpCAM/CD49f positive SUM149 breast carcinoma subpopulation HuMEC supplemented with 5% FBS and Gibco defined HuMEC supplements KAPA Stranded mRNAseq kit SUM149pos_DMSO_24h SAMN06233980 6233980 HCC1806_500nMtrametinib_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937678 GSM2459913 HCC1806 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HCC1806_500nMtrametinib_24h SAMN06233981 6233981 HCC1806_500nMtrametinib_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937679 GSM2459914 HCC1806 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HCC1806_500nMtrametinib_24h SAMN06233982 6233982 SUM149pos_DMSO_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937680 GSM2459915 EpCAM/CD49f positive SUM149 breast carcinoma subpopulation HuMEC supplemented with 5% FBS and Gibco defined HuMEC supplements KAPA Stranded mRNAseq kit SUM149pos_DMSO_24h SAMN06233983 6233983 HCC1806_DMSO_24h_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937676 GSM2459911 HCC1806 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HCC1806_DMSO_24h SAMN06233984 6233984 HCC1806_DMSO_24h_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937677 GSM2459912 HCC1806 breast carcinoma cell line RPMI 1640 supplemented with 10% FBS KAPA Stranded mRNAseq kit HCC1806_DMSO_24h SAMN06239104 6239104 SUM159_DMSO_24h_500nMtrametinib_replicate2 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937699 GSM2462678 SUM159 breast carcinoma cell line DMEM/F12 1:1 supplemented with 5% FBS, 5 µg/ml insulin, 1 µg/ml hydrocortisone KAPA Stranded mRNAseq kit SUM159_DMSO_24h_500nMtrametinib SAMN06239105 6239105 SUM159_DMSO_24h_500nMtrametinib_replicate1 Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine 9606 SRS1937698 GSM2462677 SUM159 breast carcinoma cell line DMEM/F12 1:1 supplemented with 5% FBS, 5 µg/ml insulin, 1 µg/ml hydrocortisone KAPA Stranded mRNAseq kit SUM159_DMSO_24h_500nMtrametinib